Endocrine Abstracts

Background-Aim: Urolithiasis is a frequent and recurrent pathology. Diabetes has a very important role in the formation of kidney stones. The objective of our study was to study the influence of age on the morpho-constitutional characteristics of urolithiasis in diabetic patients in southern Tunisia.Methods: This is a mono-centric retrospective and descriptive study of urinary lithiasis cases in diabetic patients. The lithiasis were identified by the mor...

Introduction: Allgrove syndrome or Triple A (3A) syndrome is a rare autosomal recessive disease characterized by alacrima, esophageal achalasia and adrenocorticotropic hormone-resistant adrenal insufficiency.Observation: A 3-year-old and 9 months patient, from a consanguineous marriage, consulted for melanoderma, with family history: sisters with an heterozygous mutation of the AAAS gene, two paternal cousins, 5 years and 22 years, followed for autism an...

Introduction: Early diagnosis is therefore important for patients with asymptomatic diabetes mellitus. The aim of this study is to validate the use of Urine Dipstick in the screening of glycosuria (Gu).Material and methods: Our study involved 30 fresh urine specimens. Urinalysis was performed by dipstick (SPINREAT®). Gu was measured by the hexokinase method (DxC800® Beckman Coulter). The gold standard to diagnose Gu was co...

Background/Aim: Since diabetes is the most common endocrine disorder and the diabetic ketoacidosis (DKA) is considered as a medical emergency, our aim was to determinate the frequency of symptoms and precipitating factors of DKA in type 1 and type 2 diabetesMethods: This is a retrospective cross-sectional descriptive study concerning all patients hospitalized in the Endocrinology Department for DKA between August 2021 to December 2022. We compared the di...

Background/Aim: Diabetic ketoacidosis (DKA) is a life-threatening acute complication of diabetes. Our aim was to study the clinical features of DKA and precipitating factors responsible for DKA in diabetic patients.Methods: This is a retrospective cross-sectional descriptive study concerning all patients hospitalized in the Endocrinology Department for DKA between August 2021 and December 2021. Initial kalemia levels (k +) on presentation were determinat...

Introduction: Lipemic specimens could be a source of significant analytical errors. The aim of this study was to examine the effect of lipid removal using ultra-centrifugation of lipemic samples, on some routine biochemistry parameters.Observation: A 53-year-old man hospitalized in endocrinology department for treatment of severe hypertriglyceridemia (21.3 mmol/l). All the patient’s routine biochemical parameters were held on AU 680®...

Introduction: Precocious puberty is characterized by the onset of signs of puberty before the usual age and can be caused by various etiologies. Congenital adrenal hyperplasia represents a rare cause of precocious puberty. Our aim was to report a case of a child with precocious puberty.Observation: A 4-year-old and 11 months patient, from a consanguineous marriage, hospitalized in the endocrinology department for precocious puberty. The clinical examinat...

Introduction: Ketoacidosis is a frequent and life-threatening complication of diabetes. Our aim was to study the Correlation between kalemia and biochemical parameters in patients with diabetic ketoacidosis.Methods: This is a retrospective descriptive study concerning all patients hospitalized in the Endocrinology Department for Diabetic Ketoacidosis (DKA) between August 2021 to December 2022. Acidosis markers were measured using an ABL 80 FLEX blood gas...

Introduction: Multiple endocrine neoplasia type 2A (MEN2A) is a rare genetic tumor syndrome due to germline mutations of the RET proto-oncogene, which is characterized by medullary thyroid cancer (MTC), pheochromocytoma, and primary hyperparathyroidism. Our aim was to report a case of a patient with MEN2.Observation: A 45-year-old patient, with a history of diabetes and corticotropic insufficiency, consulted for paresthesias. The biology showed hypercalc...